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A Ralstonia solanacearum type III effector alters the actin and microtubule cytoskeleton to promote bacterial virulence in plants

Author summary Pathogenic bacteria secrete dozens of proteins directly into plant and animal cells to interfere with host biology and promote disease. These proteins, termed effectors, target different host proteins to alter cellular processes and enable path…

2024-12-26 14:00
Mechanisms of sterilizing immunity provided by an HIV-1 neutralizing antibody against mucosal infection

Author summary Control of the HIV pandemic remains a world-wide health challenge. Although antibodies against HIV have been shown to protect from HIV infection, the precise step during mucosal acquisition of HIV infection and the mechanisms involved are not f…

2024-12-26 14:00
Drug Trials Snapshots: OHTUVAYRE

Drug Trials Snapshots: OHTUVAYRE

2024-12-23 16:49
Nerve regeneration using a Bio 3D conduit derived from umbilical cord–Derived mesenchymal stem cells in a rat sciatic nerve defect model

Human umbilical cord–derived mesenchymal stromal cells (UC-MSCs), which can be prepared in advance and are presumed to be advantageous for nerve regeneration, have potential as a cell source for Bio 3D conduits. The purpose of this study was to evaluate the n…

2024-12-23 14:00
Toxin and capsule production by Bacillus cereus biovar anthracis influence pathogenicity in macrophages and animal models

Author summary Bacillus cereus biovar anthracis (Bcbva) is a Gram-positive, spore-forming bacteria that causes anthrax-like disease in several animal species including non-human primates. It is listed as a select agent by the US Centers for Disease Control an…

2024-12-23 14:00
Discovery of Nanosota-EB1 and -EB2 as Novel Nanobody Inhibitors Against Ebola Virus Infection

Author summary Ebola virus (EBOV) poses a serious global health threat due to its high fatality rate. Current antibody-based treatments face significant challenges, including reducing mortality, addressing viral persistence in some survivors, and ensuring aff…

2024-12-23 14:00
XTX Topco Ltd Raises Stake in Femasys Inc. (NASDAQ:FEMY)

XTX Topco Ltd lifted its stake in shares of Femasys Inc. (NASDAQ:FEMY – Free Report) by 123.9% during the 3rd quarter, according to the company in its most recent filing with the Securities & Exchange Commission. The firm owned 32,535 shares of the company’s …

2024-12-23 08:40
Dentist Sentenced to 15 Years in Prison for Stealing Drugs from Patients and Performing Surgery Without Proper Pain Management

FDA-OCI, Phillip Jensen, Phillip M. Jensen, Springfield, Illinois, Rochester, Illinois

2024-12-20 20:08
Breast Implants Market Growing at 9.6% CAGR, Reaching USD 6.16 Billion by 2032 | Introspective Market Research

Breast Implants Market Size Was Valued at USD 2.96 Billion in 2023 and is Projected to Reach USD 6.16 Billion by 2032, Growing at a CAGR of 9.6% From 2024-2032. Breast Implants Market Size Was Valued at USD 2.96 Billion in 2023 and is Projected to Reach USD 6…

2024-12-20 12:36
An epitome of electricity and galvanism (1809)

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2024-12-20 00:38