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Malian field isolates provide insight into Plasmodium malariae intra-erythrocytic development and invasion

Author summary Malaria is a parasitic disease caused by Plasmodium parasite genus transmitted by Anopheles mosquitoes. Five different species are involved in human infection, and two of them have been largely studied, P. falciparum and P. vivax. However, with…

2025-01-06 14:00
Leveraging cancer mutation data to inform the pathogenicity classification of germline missense variants

Author summary Our study introduces an approach to improve the interpretation of rare genetic variation, specifically missense variants that can alter proteins and cause disease. We found that published evidence from somatic cancer sequencing studies may be r…

2025-01-06 14:00
President Chaos Presiding Over Hell on Earth

Honestly, as 2025 begins, isn’t it finally time to reimagine American history? So, what do you think of this: George Trump, Abraham Trump, Ulysses S. Trump, Franklin D. Trump, Dwight D. Trump, John F. Trump, Lyndon B. Trump, and even Richard M. and George W. …

2025-01-06 13:47
2025 NFL playoffs bracket, odds: Steelers, Ravens renew rivalry; Vikings travel to Los Angeles

Here's your first look at the opening round of the NFL playoffs

2025-01-06 13:17
What is a polar vortex, the weather event causing winter storms in the US?

The expanding of the polar vortex - an area of cold air around the Arctic - southwards is causing cold spells in the US.

2025-01-06 11:43
Polymarket Bettors Are Confident Justin Trudeau Will Resign by Friday

Duelling scoops from two of Canada's largest newspapers put Trudeau's departure as early as Monday, but Polymarket bettors aren't so sure it'll come that early.

2025-01-06 11:33
Adding To The Utility Belt: Tools Powering Grid Resiliency

As temperatures soar from the effects of climate change, energy demand escalates and the urgency to find solutions accelerates.

2025-01-06 11:30
As Humanities Fight for Support, New Journal Aims to Celebrate Their Role in Public Life

Like air, humanities-driven work is everywhere but taken for granted, so much a part of life it’s easy to overlook. A scholarly book or article about ...

2025-01-06 11:00